CPT CODEPathology/LabStatus X

CPT Code 87327Complete Billing & Coding Guide (2026)Cryptococcus neoform ag ia

Reviewed by AAPC-Certified Coders2026 Medicare Fee ScheduleCMS + AMA Sources

Medicare Payment

Non-facility · National avg

Facility

Total RVU

0.00

Global

XXX

Payment

non-facility

Work RVU

0.00

physician effort

Global Period

XXX

no post-op

Bundling Edits

NCCI pairs

Overview Payment Bundling Coding Rules FAQ

About CPT 87327

CPT 87327 is a Current Procedural Terminology code in the Pathology/Lab category maintained by the American Medical Association. The CMS short descriptor reads "Cryptococcus neoform ag ia". For the full AMA long descriptor and clinical guidance, refer to the current CPT code manual.

Documentation specificity, correct ICD-10 linkage, and modifier accuracy determine whether 87327 pays cleanly or triggers a denial. Verify CMS National Physician Fee Schedule status, applicable Medicare LCDs, and any payer-specific medical policies before submission.

Pro Tip

87327 has 4 NCCI bundling edit pairs documented. Run your scrubber against the NCCI quarterly update before submission. When clinically warranted, use modifier 59 or the X-modifiers (XE, XS, XP, XU) to bypass an indicator-1 edit, with chart documentation supporting the distinct service.

Code Properties

Global Period

XXX

Not applicable (E/M, diagnostic, etc.)

Status Indicator

Statutorily excluded.

Conversion Factor

$33.4009

CMS national rate

Effective Date

2026-04-01

per CMS publication

RVU Breakdown

Every CPT code’s Medicare payment is calculated from three Relative Value Unit components: physician work, practice expense, and malpractice. Together they multiply by the conversion factor to produce the payment amount.

RVU Composition

0.00 total RVU

Work RVU

0.00 · 0%

Physician time + skill

Practice Expense

0.00 · 0%

Office & equipment

Malpractice

0.00 · 0%

Liability insurance

Non-Facility

Private office · urgent care · ambulatory

Most billed

$0.00

0.00 RVU × $33.4009 CF

Facility

Hospital · ASC · nursing home

$0.00

0.00 RVU × $33.4009 CF

Payment = Total RVU × Conversion Factor ($33.4009) × Geographic Adjustment (GPCI). National averages shown. Actual payment varies by locality.

NCCI Bundling Edits

4 pairs

These codes trigger National Correct Coding Initiative edits when billed with 87327. An indicator of 0 means the pair cannot be unbundled. Indicator 1 means modifier 59 or X-modifiers may allow separate billing with supporting documentation.

Common Denial Risk

Billing 87327 alongside a bundled code without the correct modifier generates CARC 97 denials. Payers often flag these as audit risks. Document medical necessity for the separate service and apply modifier 59 or the appropriate X-modifier (XE, XS, XP, XU) only when clinically justified.

87206

Modifier OK

Misuse of Column Two code with Column One code

View code

88346

Modifier OK

Misuse of Column Two code with Column One code

View code

88350

Modifier OK

Misuse of Column Two code with Column One code

View code

96523

Hard bundle

CPT Manual or CMS manual coding instruction

View code

AR Recovery Note

Bundling denials on 87327 are recoverable when the edit indicator is 1 and the chart documents a distinct, separately identifiable service. Our coders verify the indicator and pick the precise X-modifier (XE, XS, XP, XU) instead of defaulting to modifier 59.

Applicable Modifiers

Modifiers commonly paired with 87327 based on its category. Apply only when the clinical circumstance warrants. Incorrect modifier use is a top audit target.

Professional component — physician interpretation/report only (no technical component)

When to use · When the physician only interprets/reads a diagnostic test performed by another entity (e.g., reading an echo performed at a hospital).

Preventive services — when the primary purpose is delivery of an evidence-based service per USPSTF A or B recommendation

When to use · Screening services (colonoscopy, mammography, etc.) to indicate the primary purpose is preventive. Waives cost-sharing under ACA.

Repeat procedure or service by same physician

When to use · When the same physician repeats the exact same procedure on the same day (e.g., repeat EKG after treatment, repeat X-ray after reduction).

Repeat procedure by another physician

When to use · When a different physician repeats the same procedure on the same day.

Repeat clinical diagnostic laboratory test on the same day for the same patient

When to use · When the same lab test is repeated on the same day for clinical reasons (not equipment malfunction).

Waiver of liability statement issued as required by payer policy (ABN on file)

When to use · Medicare: when an Advance Beneficiary Notice (ABN) has been signed by the patient for services that may not be covered.

Item or service statutorily excluded or does not meet the definition of any Medicare benefit

When to use · Service is never covered by Medicare (e.g., cosmetic procedures). May bill patient directly.

Item or service expected to be denied as not reasonable and necessary — no ABN on file

When to use · When a service is expected to be denied by Medicare and no ABN was obtained. Provider cannot bill the patient.

AR Recovery Note

Component split modifiers (26 professional, TC technical) are the most under-applied modifiers in diagnostic billing. Practices that bill global on services where they only provided the read silently invite refund requests. We split components correctly at submission.

Free 90-Day AR Recovery Audit

Find the revenue leakage in your 87327 claims.

Wrong modifier, missing documentation, bundling without justification, stale ICD-10 linkage: these are the silent revenue killers on Pathology/Lab claims. Our AAPC-certified team audits your last 90 days of 87327 claims, surfaces the recoverable dollars, and appeals them. Free, no obligation.

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FAQ

Everything about CPT 87327

What does CPT code 87327 cover?

What is the Medicare payment for CPT 87327?

The national average Medicare payment for CPT 87327 is approximately $0 in a non-facility setting and $0 in a facility setting. Actual payment varies by locality based on GPCI adjustments. Total RVU is 0 with a conversion factor of $33.4009.

What is the global period for CPT 87327?

CPT 87327 has no global period (indicator XXX). There are no post-operative day restrictions tied to this code. Refer to CMS National Physician Fee Schedule rules and any applicable NCCI edits when billing on the same date as other services.

What codes bundle with CPT 87327?

CPT 87327 has NCCI Procedure-to-Procedure edits with 4+ codes including 87206, 88346, 88350. Modifier indicator 0 means the edit cannot be bypassed. Indicator 1 means modifier 59 or X-modifiers may allow separate billing with documentation.

CMS Medicare Physician Fee ScheduleNCCI Edits · Current QuarterAMA CPT Code Set

CPT codes and descriptions are copyright of the American Medical Association. RVU values reflect current CMS publications. Actual payment varies by locality. Commercial payer rates vary by contract.

Free 90-Day AR Recovery Audit

We audit your last 90 days of claims and surface the revenue leakage: wrong modifiers, missed bundling appeals, ICD-10 specificity gaps. AAPC-certified coders. 2.49% of collections. No setup fees.

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